Joe Schmidt has handed Garry Ringrose, Billy Holland and Jack ODonoghue debuts against Canada on Saturday, in a reshuffle of his starting lineup following the historic win over New Zealand.Prodigiously-talented Leinster 21-year-old Ringrose features at outside centre in an entirely-changed starting XV from last weekends history-making 40-29 victory over New Zealand in Chicago.Munster back-five forwards Billy Holland and Jack ODonoghue will make their Test bows in the pack, with five potential debutants lying in wait on the bench. Hooker James Tracy, prop John Ryan, flanker Dan Leavy, scrum-half Luke McGrath and wing Niyi Adelokun are all now primed for their first taste of Test action this weekend.Flanker Peter OMahony captains Joe Schmidts side in his first Test turn since tearing knee ligaments in Irelands 24-9 World Cup victory over France in October 2015.Leinsters bulldozing back-rower Sean OBrien starts at openside in his first international since tearing a hamstring in Februarys 10-9 RBS 6 Nations defeat in France.Head coach Schmidt omitted senior back-row forwards OMahony and OBrien from last weekends Chicago trip, where Ireland claimed their first-ever win over New Zealand after 111 years of trying.Now both flankers will throw everything at Canada in a bid to force themselves into contention for the rematch with New Zealand in Dublin on Saturday week.Ireland head coach Schmidt hailed Ringrose as a natural player primed to transfer his free-running attacking game to the Test arena.Hes given us confidence that hes ready and I dont doubt that hes ready to get started, said Schmidt. Garrys a really natural player. He sees things ahead of other people because of how well he reads the game.And hes defensively astute too. With the experience we have around him in that backline, with Luke Marshall who went very well in South Africa, I think hopefully its a good balance.Schmidt also revealed Ulster lock Iain Henderson was close to a return, but just not quite fully fit after shoulder trouble.Former Ulster boss Mark Anscombe says Canada are searching for credibility. Canadas Kiwi head coach believes his side must utilise their Aviva Stadium platform as a sales pitch for further future fixtures against top-tier opposition.Canada sit 18th in the world rankings opposed to Irelands fifth.The boys have adapted well to what we want do to and were really looking forward to the game, Anscombe said. We have to do well on Saturday so that we get credibility so that we can face off against other tier-one teams in the future.Iain trained really well this week and we just felt that hes very close but it would be a little bit of a risk that if he got a knock he could well be out for two to three weeks, said Schmidt. This way hell definitely be fit to train fully for a whole week.Ireland team to face Canada:?Tiernan OHalloran, Craig Gilroy, Garry Ringrose, Luke Marshall, Keith Earls, Paddy Jackson, Kieran Marmion; Cian Healy, Seán Cronin, Finlay Bealham, Ultan Dillane, Billy Holland, Peter OMahony, Seán OBrien, Jack O DonoghueReplacements: James Tracy, David Kilcoyne, John Ryan, Donnacha Ryan, Dan Leavy, Luke McGrath, Joey Carbery, Niyi Adeolokun.Canada team to face Ireland: Evans (Cornish Pirates), Van der Merwe (Scarlets), Trainor (RC Vannes), Hearn (London Irish), Paris (Agen), Braid (James Bay AA), McRorie (Calgary Hornets), Sears-Duru (Glasgow Warriors), Barkwill (Castaway Wanderers), Ilnicki (Manawatu), Beukeboom (Cornish Pirates), Olmstead (Newcastle Falcons), Baillie (Balmy Beach RFC), Carpenter (Cornish Pirates, capt).Replacements: Howard (Brantford Harlequins), Brouwer (Lindsay RFC), Tierney (Section Paloise), Admir Cejvanovic (Burnaby Lake RFC), Heaton (Darlington Mowden Park), Parfrey (both James Bay AA), Blevins (Calgary Hornets). 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